TOMITA Hiroshi

写真a

Affiliation

IWATE University  Faculty of Agriculture  Department of Life Science  Course of Molecular Biomedical Sciences 

Position

Professor

Year of Birth

1966

Laboratory Address

〒0208551 4-3-5,Ueda,Morioka

Laboratory Phone number

+81-19-621-6427

Laboratory Fax number

+81-19-621-6427

Mail Address

E-mail address

Graduating School 【 display / non-display

  •  
    -
    1990.03

    Kyoto Prefectural University     Graduated

Graduate School 【 display / non-display

  •  
    -
    1992.03

    Kyoto Prefectural University    Master's Course  Completed

Degree 【 display / non-display

  • Tohoku University -  Doctor of Philosophy  1998.09.15

  • Kyoto Prefectural University -  Agriculture  1992.03.14

Campus Career 【 display / non-display

  • 2012.04
    -
    Now

    IWATE University   Abolition organization   Department of Chemistry and Bioengineering   Professor   [Duty]

External Career 【 display / non-display

  • 2012.04
    -
    2022.03

    Tohoku University Hospital   Visiting Professor  

  • 2012.01
    -
    2015.12

    RetroSense, LLC   Scientific Advisor  

  • 2008.04
    -
    2012.03

      Associate Professor  

  • 2008.04
    -
    2012.03

      Associate Professor  

  • 2004.07
    -
    2008.03

      Associate Professor (As Old Post Name)  

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Research Areas 【 display / non-display

  • Life Science / Ophthalmology

Recommended URL 【 display / non-display

 

Course Subject 【 display / non-display

  • 2012

    Advanced Neural Information Science

  • 2012

    Introduction to Chemistry and Bioengineering

  • 2012

    Basic Seminar for the first-year students

  • 2012

    Undergraduate Research

  • 2012

    Special Seminar on Chemistry and Bioengineering

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Published Papers 【 display / non-display

  • Val109 and Ile170 contribute to channel function in Guillardia theta-derived anion channelrhodopsins

    Yokoyama T, Sugano E, Tabata K, Kakizaki T, Maruoka S, Endo Y, Ozaki T, Fukuda T, Bai L, Tomita H.

    Scientific Reports ( Springer Nature )  16 ( 1 ) - - -   2026.04  [Refereed]

    Academic Journal  Multiple authorship

    DOI

  • RNA-seq analysis of neuronal gene expression changes in rat Muller glia-derived rMC-1 cells under treatment with compound promoting photoreceptor differentiation

    Endo Y, Sugano E, Seko Y, Fukuda T, Tabata K, Kakizaki T, Maruoka S, Yokoyama T, Ozaki T, Bai L, Tomita H

    Neuroglia ( MDPI )  7 ( 1 ) 8   2026.03  [Refereed]

    Academic Journal  Multiple authorship

    DOI

  • Magnetoencephalography measurement of somatosensory responses in optogenetic rats using optically pumped magnetometer

    Kanta Komuro; Motofumi Fushimi ; Yuta Kainuma; Tingyu Zhu; Seiko Funatani; Shinichi Chikaki; Hiroshi Tomita; Hiromu Yawo ; Masaki Sekino

    AIP Advances ( AIP Publishing )    2026.03  [Refereed]

    Academic Journal  Multiple authorship

  • Direct reprogramming of Müller glia into photoreceptors via multiple transcription factors and small molecules: molecular mechanisms and transcriptomic analysis

    Endo Yuka、 Sugano Eriko、 Seko Yuko、 Fukuda Tomokazu、 Tabata Kitako、 Kakizaki Taira、 Maruoka Shu、 Yokoyama Takanori、 Mori Hanaho、 Ozaki Taku、 Bai Lanlan、 Tomita Hiroshi

    In Vitro Cell Dev Biol Anim   62 ( 5 ) 685 - 703   2026.02  [Refereed]

    Academic Journal  Multiple authorship

    DOI

  • Pyrroloquinoline Quinone Protects Against Light-Induced Retinal Damage in Association with the Suppression of c-Fos Signalling

    Hinata Ozawa, Eriko Sugano, Kitako Tabata, Taira Kakizaki, Akimune Sato, Yoshihiro Takai, Kohei Sone, Miwako Shidomi, Yuki Ishii, Akito Saito, Kentaro Totuka, Taku Ozaki, Tomokazu Fukuda, Lanlan Bai, Hiroshi Tomita

    Int J Mol Sci . ( MDPI )  27 ( 4 ) 1929   2026.02  [Refereed]

    Academic Journal  Multiple authorship

    DOI

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Books 【 display / non-display

  • OPTOGENETICS: From Neuronal Function to Mapping & Disease Biology

    Tomita H, Sugano E

    Cambridge University Book  2017.06 ISBN: 978-110705301

    Scholarly Book

  • Light-Sensing Proteins and their Applications: Establishment of gene therapy using Channelrhodopsin-2 to treat blindness

    Sugano E, Tomita H.

    Springer  2015.02 ISBN: 978-4-431-555

    Scholarly Book

  • Gene Therapy - Tools and Potential Applications

    Tomita H, Sugano E, Isago H, Murayama N, Tamai M

    InTech  2013.02 ISBN: 978-953

    Academic Books

  • Retinal Degeneration and Regeneration

    Tomita H, Sugano E, Abe T, Tamai M

    Plenum Publishers  2003.01

    Academic Books

  • Retinal Degeneration

    Abe T, Tomita H, Ohashi T, Yamada K, Akaishi K, Yoshida M, Sato M, Tamai M

    Plenum Publishing Corporation  1999.01

    Academic Books

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Review Papers 【 display / non-display

  • Channelrhodopsins provide a breakthrough insight into strategies for curing blindness

    Tomita H, Sugano E, Isago H, Tamai M

    J Genetics ( Cambridge University Press )  88   409 - 415   2009.12

    Academic Journal  

  • Optogenetics-mediated gene therapy for retinal diseases

    Tomita H, Sugano E

    Adv Exp Med Biol ( Springer )  1293   535 - 543   2021.01

    Academic Journal  

    DOI

Presentations 【 display / non-display

  • Selected from posters Excessive synaptic turnover and inter-synapse interactions are modified by oxytocin in the dorsomedial prefrontal cortex in an autism model marmoset

    Oral Presentation(General) 

    2023.02
     
     

  • Excessive synaptic turnover and inter-synapse interactions are modified by oxytocin in the dorsomedial prefrontal cortex in an autism model marmoset

    Oral Presentation(General) 

    2022.06
    -
    2022.07

  • International Symposium 4:Gene therapy using our developed mVChR1 gene for Retinitis Pigmentosa

    Symposium, Workshop, Panelist (Nomination)  Eriko Sugano, Kitako Tabata, Yoshito Watanabe, Makoto Tamai, Hiroshi Tomita

    2019.04
     
     

  • [視機能再建への挑戦]緑藻由来遺伝子を用いた視覚再生のための遺伝子治療研究

    Oral Presentation(Guest/Special) 

    2018.06
     
     

  • possibilities of optogenetic mediated retinal gene therapies

    Oral Presentation(Guest/Special)  Tomita H, Sugano E

    2018.06
     
     

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Academic Awards Received 【 display / non-display

  • 2021.11.06

  • International Research Collaborators Award

    2017.06.07

    All winners: University of Tennessee Health Science Center

  • 2015.05.12

  • Best Scientific Poster Award

    2009.01.20

  • Best Scientific Poster Award

    2009.01.20

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Industrial Property 【 display / non-display

  • Modified Channel Rhodopsin

    Patent

    Application number PCT/JP2019/036252  Publication number WO 2020/059675 A1 

    Application date: 2019.09.15

    Publication date: 2020.03.26

  • Light-receiving channel rhodopsin having improved expression efficiency

    Patent

    Publication number PCT/JP2010/063786  Registration number US 8,754,048 B2

Resource can be provided 【 display / non-display

  • Adeno-associated virus vector

    Making a construct of adeno-associated virus vectors for the researches of gene therapies