KIMURA Ken-ichi

写真a

Affiliation

IWATE University  Faculty of Agriculture  Department of Biological Chemistry and Food Science 

Position

Professor

Year of Birth

1959

Laboratory Address

〒0208550 3-18-8 Ueda, Morioka

Laboratory Phone number

+81-19-621-6124

Laboratory Fax number

+81-19-621-6124

Mail Address

E-mail address

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Graduating School 【 display / non-display 】

  • 　
    -
    1982.03

    Tohoku University   Faculty of Agriculture   Agricultural Chemistry   Graduated

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Graduate School 【 display / non-display 】

  • 　
    -
    1984.03

    Tohoku University  Graduate School, Division of Agriculture  Agricultural Chemistry  Master's Course  Completed

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Degree 【 display / non-display 】

  • Tohoku University -  Doctor of agriculture  1990.12

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Campus Career 【 display / non-display 】

  • 2001.12
    -
    2007.03

    IWATE University   Faculty of Agriculture   Agro-bioscience   Food and Health Science   Associate Professor (As Old Post Name)   [Duty]

  • 2007.04
    -
    2010.09

    IWATE University   Faculty of Agriculture   Associate Professor   [Duty]

  • 2010.10
    -
    Now

    IWATE University   Professor   [Duty]

  • 2015.04
    -
    2016.03

    IWATE University   Faculty of Agriculture   Biological Chemistry and Food Science   Department Head   [Concurrently]

  • 2016.04
    -
    2018.03

    IWATE University   Faculty of Agriculture   Department of Biological Chemistry and Food Science   Department Head   [Concurrently]

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External Career 【 display / non-display 】

  • 2000.04
    -
    2001.11

      Head of Quality Control Group, Iwate Pharmaceutical Product Plant, Snow Brand Milk Products, Co. Ltd.  

  • 1998.02
    -
    1998.03

      Visiting Researcher, Southampton University  

  • 1984.04
    -
    2000.01

      Researcher, Associate Researcher, Chief Researcher, Research Institute of Life Science, Snow Brand Milk Products, Co. Ltd.  

  • 1984.04
    -
    1986.03

      Contract Researcher, The Physical and Chemical Research  

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Research Areas 【 display / non-display 】

  • Life Science / Applied biochemistry

  • Nanotechnology/Materials / Chemistry and chemical methodology of biomolecules

  • Life Science / Bioorganic chemistry

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Course Subject 【 display / non-display 】

  • 2004

    Regulations relating Food Production

  • 2004

    Food and Health Science Seminar

  • 2004

    Food Hygiene Laboratory

  • 2004

  • 2004

    Basic Food and Health Science Laboratory

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Research Career 【 display / non-display 】

  • Chemical biology of natural products derived from microorganisms, food ingredients, and plant.

    Periods of research：

    2001.12
    -
    Now

    Keywords : Chemical biology, Natural product, Life-oriented diseases

    Style of Research： Collaboration in Japan

    Research Program： (not selected)  

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Published Papers 【 display / non-display 】

  • 3,6-Epidioxy-1,10-bisaboladiene induces ferroptosis-like cell death through lipid peroxidation.

    N. Usukhbayar, Y. Takano, S. Uesugi, M. Muroi, H. Osada, K. Kimura

    Free Radic. Res.     2023.05  [Refereed]

    Bulletin of University, Institute, etc.  Multiple authorship

  • Bidesmosidic and monodesmosidic triterpenoid saponins from the grain of Amaranthus hypochondriacus.

    K. Fukuhara, A. Shiraishi, K. Kimura, A. Yano

    Phytochem. Lett.     2024.01  [Refereed]

    Bulletin of University, Institute, etc.  Multiple authorship

  • 3,6-Epidioxy-1,10-bisaboladiene and sulfasalazine synergistically induce ferroptosis-like cell death in human breast cancer cell lines.

    N. Usukhbayar, S. Uesugi, K. Kimura

    Biosci. Biotechnol. Biochem.     2023.12  [Refereed]

    Bulletin of University, Institute, etc.  Multiple authorship

  • A. Yano, S. Yuki, A. Shiraishi, M. Hakozaki, Y. Kanno, K. Kimura, S. Uesugi, Golden berry leaf extract containing withanolides suppresses TNF-α and IL-17 induced IL-6 expression in HeLa Cells.

    A. Yano, S. Yuki, A. Shiraishi, M. Hakozaki, Y. Kanno, K. Kimura, S. Uesugi

    Biosci. Biotechnol. Biochem.     2023.09  [Refereed]

    Bulletin of University, Institute, etc.  Multiple authorship

  • Cytotoxicity and induction of G1 phase cell cycle arrest in human acute promyelocytic leukemia HL60 cells by indole alkaloids isolated from Dialium corbisieri seeds.

    A. Dradre, T. Koseki, N. Usukhbayar, K. Kimura, Y. Shiono

    Biosci. Biotechnol. Biochem.     2023.08  [Refereed]

    Bulletin of University, Institute, etc.  Multiple authorship

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Books 【 display / non-display 】

  • Tea as a Food Ingredient, Properties, Processing, and Health Aspects (Edited by J. Yin, Z, Fu and Y. Xu), Chapter 5. Japanese green tea: Processing, Chemical Properties and Health Benefits.

    S. Koide and K. Kimura

    2022.08

    Scholarly Book

  • Endophytic Microorganisms as a Source of Bioactive Compounds.

    Shiono, Y. and Kimura, K.

    2011.10

    Academic Books

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Review Papers 【 display / non-display 】

  • Liposidomycin, the first reported nucleoside antibiotic inhibitor of peptidoglycan biosynthesis translocase I: The related compounds with a perspective on their application to new antibiotics Bacterial polyoxin, named loposidomycin, a potent inhibitor of peptidoglycan biosynthesis.

    K. Kimura

    J. Antibiot ( Nature Publishing Group )  72   877 - 889   2019.12

    Academic Journal  

  • Studies of novel bioprobes isolated from rare natural sources using mutant yeasts.

    K. Kimura

    J. Antibiot. ( Nature Publishing Group )  72 ( 8 ) 579 - 589   2019.08

    Academic Journal  

  • Antimicrobial nucleoside antibiotics targetting cell wall assembly: Recent advances in structure-function studies and nucleoside biosynthesis.

    Winn, M., Goss, R. J. M., Kimura, K. and Bugg, T. D. H.

    Natural Products Report ( Royal Society of Chemistry )  27   279 - 304   2010.01

    In-House Magazine  

  • Barminomycin, a model for the development of new anthracyclines.

    K. Kimura, D. M. Spencer, R. Bilardi, L. P. Swift, A. J. Box, R. T. Brownlee, S. M. Cutts and D. R. Phillips

    Anti-cancer Agents in Medicinal Chemistry ( Bentham Science Publication Ltd. )  10   38 - 43   2010.01

    In-House Magazine  

  • Recent advances in antimicrobial nucleoside antibiotics targeting cell wall biosynthesis.

    Kimura, K. and Bugg, T.D.H.

    Nat. Prod. Rep. ( Royal Society of Chemistry )  20   252 - 273   2003.03

    Others  

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Academic Awards Received 【 display / non-display 】

  • 2023.12.02

  • 2022.03.15

  • 2019.06.07

  • 2019.03.24

  • 2018.12.22

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Preferred joint research theme 【 display / non-display 】

  • Screening of new biological active substance from natural resources such as food ingredients, microorganism and plant.

    Joint research form : Cooperative Research with Industry-University research organizations and/or private agencies.

    Possible form for cooperating Industry-Academia Collaboration : Cooperative Research

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