研究者詳細 - 尾﨑　拓

論文 - 尾﨑　拓

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Mitochondrial calpain-1 truncates ATP synthase beta subunit

Yusaku Chukai, Nanami Furukawa, On Kosegawa, Lanlan Bai, Eriko Sugano, Tomokazu Fukuda, Hiroshi Tomita, Taku Ozaki

Biochemical and Biophysical Research Communications 765 151829 2025年06月 [査読有り]

国際的学術誌共著・分担

Intranasal administration of ergothioneine improves memory in a mouse model of multiple system atrophy.

Kazuto Kimura, Makoto Timon Tanaka, Yasuo Miki, Tomonori Furukawa, Shuya Kasai, Taku Ozaki, Fumiaki Mori, Eri Shibuya, Koichi Wakabayash

Biochemical and Biophysical Research Communications 756 151550 2025年04月 [査読有り]

国際的学術誌共著・分担

DOI

Detection of the nuclear translocation of androgen receptor using quantitative and automatic cell imaging analysis.

Lanlan Bai, Tao Wu, Mizuki Fukasawa, Sayo Kashiwagi, Haruka Tate, Taku Ozaki, Eriko Sugano, Hiroshi Tomita, Tsuyoshi Ishii, Takuya Akashi, Tomokazu Fukuda

Tissue and Cell 93 102631 2025年04月 [査読有り]

国際的学術誌共著・分担

DOI

Enhanced auditory responses in visual cortex of blind rats using intrinsic optical signal imaging.

Shu Maruoka, Eriko Sugano, Ryunosuke Togawa, Norihiro Katayama, Kitako Tabata, Naoto Yoshizawa, Ryohei Morita, Yuya Takita, Taku Ozaki, Tomokazu Fukuda, Lanlan Bai, Hiroshi Tomita

Scientific Reports 14 ( 1 ) 24740 2024年11月 [査読有り]

国際的学術誌共著・分担

DOI

Adipose-derived cells surpass muscle-derived cells in primary cell isolation efficacy.

Lanlan Bai, Ken Sawai, Tetsuta Tani, Mayuko Nakai, Himari Matsusaka, Keiko Ito, Hiroshi Tomita, Eriko Sugano, Taku Ozaki, Tomokazu Fukuda

In Vitro Cellular & Developmental Biology-Animal 2024年10月 [査読有り]

国際的学術誌共著・分担

DOI

Intranasal administration of trehalose reduces α-synuclein oligomers and accelerates α-synuclein aggregation.

Makoto T. Tanaka, Yasuo Miki, Fumiaki Mori, Tomoya Kon, Tomonori Furukawa, Shuji Shimoyama, Yota Tatara, Taku Ozaki, Conceicao Bettencourt, Thomas T. Warner, Koichi Wakabayashi

Brain Communications ( Oxford University Press ) 6 ( 4 ) fcae193 2024年08月 [査読有り]

国際的学術誌共著・分担

DOI

Proteolysis of mitochondrial calpain-13 in cerebral ischemia-reperfusion injury

Yusaku Chukai, Toru Sudo, Tomokazu Fukuda, Hiroshi Tomita, Eriko Sugano, Taku Ozaki

Biochemistry and Biophysics Reports ( Elsevier ) 39 101768 2024年07月 [査読有り]

国際的学術誌共著・分担

DOI

A New Strategy for the Synthesis of (+)-Crambescin B Decarboxylate

Yuki Yonekura, Masahide Konno, Taku Ozaki, Atsuo Nakazaki

EurJOC (European Journal of Organic Chemistry) 27 ( 19 ) e202400176 2024年05月 [査読有り]

国際的学術誌共著・分担

DOI

Establishment of immortalized Egyptian Rousettus bat cell lines

Lanlan Bai, Tetsuya Tani, Takeshi Kobayashi, Ryotaro Nouda, Yuta Kanai, Yusuke Sano, Kazutoshi Takami, Hiroshi Tomita, Eriko Sugano, Taku Ozaki, Tohru Kiyono, Tomokazu Fukuda

FEBS Open Bio 14 ( 4 ) 598 - 612 2024年04月 [査読有り]

国際的学術誌共著・分担

DOI PubMed

Characterization of common minke whale (Balaenoptera acutorostrata) cell lines immortalized with the expression of cell cycle regulators

Aya Sekine, Genta Yasunaga, Soichiro Kumamoto, So Fujibayashi, Izzah Munirah, Lanlan Bai, Tetsuya Tani, Eriko Sugano, Hiroshi Tomita, Taku Ozaki, Tohru Kiyono, Miho Inoue-Murayama, Tomokazu Fukuda

Advanced Biology 8 ( 3 ) 2300227 2024年03月 [査読有り]

国際的学術誌共著・分担

DOI PubMed

Role of calpain-5 in cerebral ischemia and reperfusion injury

Yusaku Chukai, Ginga Ito, Yasuo Miki, Koichi Wakabayashi, Ken Itoh, Eriko Sugano, Hiroshi Tomita, Tomokazu Fukuda, Taku Ozaki

BBA-General Subjects 1868 130506 2024年01月 [査読有り]

国際的学術誌共著・分担

DOI PubMed

Evaluation of Local Retinal Function in Light-Damaged Rats Using Multifocal Electroretinograms and Multifocal Visual Evoked Potentials

Yuya Takita, Eriko Sugano, Kazuya Kitabayashi, Kitako Tabata, Akito Saito, Takanori Yokoyama, Reina Onoguchi, Tomokazu Fukuda, Taku Ozaki , Lanlan Bai, Hiroshi Tomita

International Journal of Molecular Sciences 24 ( 22 ) 16433 2023年11月 [査読有り]

国際的学術誌共著・分担

DOI PubMed

Novel dicarbonyl metabolic pathway via mitochondrial ES1 possessing glyoxalase III activity

Ginga Ito, Yota Tatara, Ken Itoh, Miwa Yamada, Tetsuro Yamashita, Kimitoshi Sakamoto, Takayuki Nozaki, Kinji Ishida, Yui Wake, Takehito Kaneko, Tomokazu Fukuda, Eriko Sugano, Hiroshi Tomita, Taku Ozaki

BBA Advances 3 100092 2023年05月 [査読有り]

国際的学術誌共著・分担

DOI PubMed

Sheep-derived cell immortalization through the expression of cell cycle regulators and biological characterization using transcriptomes

Noe Kikuchi, Himari Matsusaka, Lanlan Bai, Hiroaki Sano, Takahiro Eitsuka, Kiyotaka Nakagawa, Eriko Sugano, Taku Ozaki, Hiroshi Tomita, Toru Kiyono, Tomokazu Fukuda

Cell Biology International 2023年05月 [査読有り]

国際的学術誌共著・分担

DOI

Properties of a single amino acid residue in the third transmembrane domain determine the kinetics of ambient light-sensitive channelrhodopsin

Akito Hatakeyama, Eriko Sugano, Tatsuki Sayama, Yoshito Watanabe, Tomoya Suzuki, Kitako Tabata, Yuka Endo, Tetsuya Sakajiri, Tomokazu Fukuda, Taku Ozaki, Hiroshi Tomita

International Journal of Molecular Sciences ( MDPI ) 24 ( 5 ) 5054 2023年03月 [査読有り]

国際的学術誌共著・分担

DOI

Comprehensive transcriptome data to identify downstream genes of testosterone signalling in dermal papilla cells

Himari Matsusaka, Tao Wu, Kai Furuya, Tomoe Yamada-Kato, Lanlan Bai, Hiroshi Tomita, Eriko Sugano, Taku Ozaki, Tohru Kiyono, Isao Okunishi, Tomokazu Fukuda

Scientific Data ( Springer Nature ) 9 ( 1 ) 731 2022年11月 [査読有り]

国際的学術誌共著・分担

DOI

Phosphorylation of Tau at Threonine 231 in Patients With Multiple System Atrophy and in a Mouse Model

Makoto Timon Tanaka, Kunikazu Tanji, Yasuo Miki, Taku Ozaki, Fumiaki Mori, Hideki Hayashi, Akiyoshi Kakita, Koichi Wakabayashi

Journal of Neuropathology & Experimental Neurology ( Oxford University Press ) 81 ( 11 ) 920 - 930 2022年10月 [査読有り]

国際的学術誌共著・分担

DOI

SIG-1451, a Novel, Non-Steroidal Anti-Inflammatory Compound, Attenuates Light-Induced Photoreceptor Degeneration by Affecting the Inflammatory Process

Yuki Kikuchi, Eriko Sugano, Shiori Yuki, Kitako Tabata, Yuka Endo, Yuya Takita, Reina Onoguchi, Taku Ozaki, Tomokazu Fukuda, Yoshihiro Takai, Takahiro Kurose, Koichi Tanaka, Yoichi Honma, Eduardo Perez, Maxwell Stock, José R. Fernández, Masanori Tamura, Michael Voronkov, Jeffry B. Stock, Hiroshi Tomita

International Journal of Molecular Sciences ( MDPI ) 23 8802 2022年08月 [査読有り]

国際的学術誌共著・分担

DOI

Involvement of autophagic protein DEF8 in Lewy bodies

Makoto Timon Tanaka, Yasuo Miki, Conceiçao Bettencourt, Taku Ozaki, Kunikazu Tanji, Fumiaki Mori, Akiyoshi Kakita, Koichi Wakabayashi

Biochemical and Biophysical Research Communications ( Elsevier ) 623 170 - 175 2022年07月 [査読有り]

国際的学術誌共著・分担

DOI

Lentiviral expression of calpain‐1 C2‐like domain peptide prevents glutamate‐induced cell death in mouse hippocampal neuronal HT22 cells

Takenori Oikawa, Tomokazu Fukuda, Tetsuro Yamashita, Hiroshi Tomita, Taku Ozaki

In Vitro Cellular & Developmental Biology-Animal 58 289 - 294 2022年04月 [査読有り]

国際的学術誌共著・分担

DOI

Mitochondrial localization of calpain-13 in mouse brain

Eiji Funajima, Ginga Ito, Eri Ishiyama, Kinji Ishida, Taku Ozaki

Biochemical and Biophysical Research Communications 609 149 - 155 2022年04月 [査読有り]

国際的学術誌共著・分担

DOI

Mitochondrial calpain-5 truncates caspase-4 during endoplasmic reticulum stress

Yusaku Chukai, Ginga Ito, Masahide Konno, Yuri Sakata, Taku Ozaki

Biochemical and Biophysical Research Communications 608 156 - 162 2022年03月 [査読有り]

国際的学術誌共著・分担

DOI

Inducible systemic Gcn1 deletion in mice leads to transient body weight loss upon tamoxifen treatment associated with changes of fat and liver glycogen storage

Jun Liu, Shuya Kasai, Yota Tatara, Hiromi Yamazaki, Junsei Mimura, Seiya Mizuno, Fumihiro Sugiyama, Satoru Takahashi, Tsubasa Sato, Taku Ozaki, Kunikazu Tanji, Koichi Wakabayashi, Hayato Maeda, Hiroki Mizukami, Yasuhiro Shinkai, Yoshito Kumagai, Hirofumi Tomita, Ken Itoh

International Journal of Molecular Sciences 23 3201 2022年03月 [査読有り]

国際的学術誌共著・分担

DOI

Detailed chromosome analysis of wild-type, immortalized fibroblasts with SV40T, E6E7, combinational introduction of cyclin dependent kinase 4, cyclin D1, telomerase reverse transcriptase

Haruka Takada, Tomisato Miura, So Fujibayashi, Naomi Sasaki, Kouhei Takahashi, Eriko Sugano, Hiroshi Tomita, Taku Ozaki, Tohru Kiyono, Mitsuaki A Yoshida, Tomokazu Fukuda

in Vitro Cellular & Developmental Biology - Animal 57 ( 10 ) 998 - 1005 2021年12月 [査読有り]

国際的学術誌共著・分担

DOI

Immoritalization of cells derived from domestic dogs through expressing mutant cyclin-dependent kinase 4, cyclin D1, and telomerase reverse transcriptase

Izzah Munirah, Taku Ozaki, Aya Sekine, Motoko Morimoto, Mayu Sugawara, Haruka Takada, Eriko Sugano, Hiroshi Tomita, Tohru Kiyono, Tomokazu Fukuda

Cytotechnology 2021年11月 [査読有り]

国際的学術誌共著・分担

DOI

Development of an optogenetic gene sensitive to daylight and its implications in vision restoration

Yoshito Watanabe, Eriko Sugano, Kitako Tabata, Akito Hatakeyama, Tetsuya Sakajiri, Tomokazu Fukuda, Taku Ozaki,Tomoya Suzuki, Tatsuki Sayama, Hiroshi Tomita.

npj Regenerative Medicine 6 ( 1 ) 64 2021年10月 [査読有り]

国際的学術誌共著・分担

DOI

Calpain-1 C2L domain peptide protects mouse hippocampus-derived neuronal HT22 cells against glutamate-induced oxytosis

Mayu Sugawara, Takumi Abe, Shuya Kasai, Ken Itoh, Taku Ozaki

Biochemistry and Biophysics Reports 27 101101 2021年08月 [査読有り]

国際的学術誌共著・分担

DOI

Phototoxicities caused by continuous light exposure were not induced in retinal ganglion cells transduced by an optogenetic gene.

Kitako Tabata, Eriko Sugano, Akito Hatakeyama, Yoshito Watanabe, Tomoya Suzuki, Taku Ozaki, Tomokazu Fukuda, Hiroshi Tomita.

International Journal of Molecular Sciences 22 ( 13 ) 6732 2021年06月 [査読有り]

国際的学術誌共著・分担

DOI

Characterization of mitochondrial calpain-5

Yusaku Chukai, Takeshi Iwamoto, Ken Itoh, Hiroshi Tomita, Taku Ozaki

Biochimica et Biophysica Acta - Molecular Cell Research ( Elsevier ) 1868 118989 2021年02月 [査読有り]

国際的学術誌共著・分担

DOI

Geranylgeranyl acetone prevents glutamate-induced cell death in HT- 22 cells by increasing mitochondrial membrane potential

Eriko Sugano, Yuka Endo, Akihisa Sugai, Yuki Kikuchi, Kitako Tabata, Taku Ozaki, Takahiro Kurose, Yoshihiro Takai, Yoko Mitsuguchi, Yoichi Honma, Hiroshi Tomita

European Journal of Pharmacology 883 173193 2020年07月 [査読有り]

国際的学術誌共著・分担

DOI

Ribosome binding protein GCN1 regulates the cell cycle and cell proliferation and is essential for the embryonic development of mice.

Hiromi Yamazaki, Shuya Kasai, Junsei Mimura, Peng Ye, Atsushi Inose-Maruyama, Kunikazu Tanji, Koichi Wakabayashi, Seiya Mizuno, Fumihiro Sugiyama, Satoru Takahashi, Tsubasa Sato, Taku Ozaki, Douglas R. Cavener, Masayuki Yamamoto, Ken Itoh

PLoS Genetics 16 ( 4 ) e1008693 2020年04月 [査読有り]

国際的学術誌共著・分担

DOI

Data on mitochondrial ultrastructure of photoreceptors in pig, rabbit, and mouse retinas

Taku Ozaki, Shinto Utsumi, Takeshi Iwamoto, Makoto Tanaka, Hiroshi Tomita, Eriko Sugano, Eri Ishiyama, Kinji Ishida

Data in Brief 30 105544 2020年04月 [査読有り]

国際的学術誌共著・分担

DOI

Presence of ES1 homolog in the mitochondrial intermembrane space of porcine retinal cells

Shinto Utsumi, Kimitoshi Sakamoto, Tetsuro Yamashita, Hiroshi Tomita, Eriko Sugano, Kinji Ishida, Eri Ishiyama, Taku Ozaki

Biochemical and Biophysical Research Communications 524 ( 3 ) 542 - 548 2020年01月 [査読有り]

国際的学術誌共著・分担

DOI

Emerging Regulatory Role in Nrf2 in Iron, Heme, and Hemoglobin Metabolism in Physiology and Disease.

Shuya Kasai, Junsei Mimura, Taku Ozaki, Ken Itoh

Frontiers in Veterinary Science 5 242 2018年10月 [査読有り]

国際的学術誌共著・分担

DOI

Presence of calpain-5 in mitochondria

Takeshi Iwamoto, Eri Ishiyama, Kinji Ishida, Tetsuro Yamashita, Hiroshi Tomita, Taku Ozaki

Biochemical and Biophysical Research Communications 504 ( 2 ) 454 - 459 2018年09月 [査読有り]

国際的学術誌共著・分担

DOI

Kinetic profiles of photocurrents in cells expressing two types of channelrhodopsin genes.

Yoshito Watanabe, Eriko Sugano, Kitako Tabata, Taku Ozaki, Takehito Saito, Makoto Tamai, Hiroshi Tomita

Biochemical and Biophysical Research Communications 496 814 - 819 2018年01月 [査読有り]

国際的学術誌共著・分担

DOI

The physiological accumulation of mutant fibroin light chains induces an unfolded protein response in the posterior silk gland of the Sericin cocoon Nd-sD strain of silkworm Bombyx mori.

Tadashi Takahashi, Masao Miyazaki, Shin-ichiro Kidou, Yoshiki Matsui, Ying An, Taku Ozaki, Kochi Suzuki, Tetsuro Yamashita

Journal of Insect Biotechnology and Sericology 86 105 - 112 2017年07月 [査読有り]

国際的学術誌共著・分担

DOI

Visual responses of photoreceptor-degenerated rats expressing two different types of channelrhodopsin genes.

Masatoshi Sato, Eriko Sugano, Kitako Tabata, Kei Sannohe, Yoshito Watanabe, Taku Ozaki, Makoto Tamai, Hiroshi Tomita

Scientific Reports 7 41210 2017年01月 [査読有り]

国際的学術誌共著・分担

DOI

The protection of rat retinal ganglion cells from ischemia/reperfusion injury by the inhibitory peptide of mitochondrial µ-calpain

Taku Ozaki, Tetsuro Yamashita, Hiroshi Tomita, Eriko Sugano, Sei-ichi Ishiguro

Biochemical and Biophysical Research Communications 478 ( 4 ) 1700 - 1705 2016年09月 [査読有り]

国際的学術誌共著・分担

DOI

Improved transduction efficiencies of adeno-associated virus vectors by synthetic cell-permeable peptides.

Kitako Tabata, Eriko Sugano, Fumika Murakami, Tetsuro Yamashita, Taku Ozaki, Hiroshi Tomita

Biochemical and Biophysical Research Communications 478 ( 4 ) 1732 - 1738 2016年09月 [査読有り]

国際的学術誌共著・分担

DOI

HSP90 regulation of P2X7 receptor function requires an intact cytoplasmic C-terminus.

Keisuke Migita, Taku Ozaki, Shuji Shimoyama, Junko Yamada, Yoshikazu Nikaido, Tomonori Furukawa, Yuko Shiba, Terrance M. Egan, Shinya Ueno

Molecular Pharmacology 90 ( 2 ) 116 - 126 2016年08月 [査読有り]

国際的学術誌共著・分担

DOI

Cell proliferation inhibition by sericin from the wild silkworm, Cricula trifenestrata.

Wenqi Liu, Mayumi Karimazawa, Taku Ozaki, Ying An, Masao Miyazaki, Koichi Suzuki, Ken-ichi Tsutsumi, Tetsuro Yamashita

Advances in Biological Chemistry 6 28 - 33 2016年02月 [査読有り]

国際的学術誌共著・分担

DOI

Delivery of topically applied calpain inhibitory peptide to the posterior segment of the rat eye

Taku Ozaki, Mitsuru Nakazawa, Tetsuro Yamashita, Sei-ichi Ishiguro

PLoS ONE 10 ( 6 ) e0130986 2015年06月 [査読有り]

国際的学術誌共著・分担

DOI

Emerging functional cross-talk between the Keap1-Nrf2 system and mitochondria.

Ken Itoh, Peng Ye, Tomoh Matsumiya, Kunikazu Tanji, Taku Ozaki

Journal of Clinical Biochemistry and Nutrition 56 ( 2 ) 91 - 97 2015年03月 [査読有り]

国際的学術誌共著・分担

DOI

Restoration of the majority of the visual spectrum by using modified Volvox channelrhodopsin-1.

Hiroshi Tomita, Eriko Sugano, Namie Murayama, Taku Ozaki, Fumiaki Nishiyama, Kitako Tabata, Maki Takahashi, Takehiko Saito, Makoto Tamai

Molecular Therapy 22 ( 8 ) 1434 - 1440 2014年08月 [査読有り]

国際的学術誌共著・分担

DOI

Protection of cone photoreceptor M-opsin degradation with 9-cis-β-carotene-rich alga Dunaliella bardawil in Rpe65-/- mouse retinal explant culture

Taku Ozaki, Mitsuru Nakazawa, Takashi Kudo, Satoshi Hirano, Kaori Suzuki, Sei-ichi Ishiguro

Current Eye Research 39 ( 12 ) 1221 - 1231 2014年07月 [査読有り]

国際的学術誌共著・分担

DOI

Phosphorylation of serine 349 of p62 in Alzheimer’s disease brain

Kunikazu Tanji, Yasuo Miki, Taku Ozaki, Atsushi Maruyama, Hidemi Yoshida, Junsei Mimura, Tomoh Matsumiya, Fumiaki Mori, Tadaatsu Imaizumi, Ken Itoh, Akiyoshi Kakita, Hitoshi Takahashi and Koichi Wakabayashi

Acta Neuropathologica Communications 2 50 2014年05月 [査読有り]

国際的学術誌共著・分担

DOI

Periosteum-derived cells respond to mechanical stretch and activate Wnt and BMP signaling pathways.

Ryohei Ito, Tomoh Matsumiya, Takao Kon, Norihiko Narita, Kosei Kubota, Hirotaka Sakai, Taku Ozaki, Tadaatsu Imaizumi, Wataru Kobayashi, Hiroto Kimura

Biomedical Research 35 ( 1 ) 69 - 79 2014年02月 [査読有り]

国際的学術誌共著・分担

DOI

Decrease of ATP by mitochondrial m-calpain inhibitory peptide in the rat retinas

Taku Ozaki, Mitsuru Nakazawa, Tetsuro Yamashita, Hiroshi Tomita, Yuichi Ebina, Sei-ichi Ishiguro

Cell Structure and Function 38 ( 2 ) 207 - 223 2013年08月 [査読有り]

国際的学術誌共著・分担