Published Papers - NISHIMUKAI Megumi

Improvement of solubility of phospholipase D from Streptomyces antibioticus in recombinant Escherichia coli and its application for the enzymatic synthesis of a non-natural plasmalogen

Riko Yamaguchi , Shamoli Akter , Aki Kanehama , Takahiro Iwamoto , Meme Hasegawa , Akeno Ito , Megumi Nishimukai , Miwa Yamada , Akiko Kashiwagi

Letters in Applied Microbiology     2023.04  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

DOI

The levels of plasma plasmalogen in retired female rats decrease by ovariectomy and intake of cholesterol-diet

Kiwa Hashiguchi, Takuma Kikuchi, Takuya Mizokami, Masao Sato, Megumi Nishimukai

Bioscience, Biotechnology, and Biochemistry     2022.09  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Dietary Lactobacillus-derived exopolysaccharide enhances immune checkpoint blockade therapy

Hirotaka Kawanabe-Matsuda, Kazuyoshi Takeda, Marie Nakamura, Seiya Makino, Takahiro Karasaki, Kazuhiro Kakimi, Megumi Nishimukai, Tatsukuni Ohno, Jumpei Omi, Kuniyuki Kano, Akiharu Uwamizu, Hideo Yagita, Ivo Gomperts Boneca, Gerard Eberl, Junken Aoki, Mark J Smyth, Ko Okumura

Cancer Discovery     OF1 - OF20   2022.05  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

DOI

Lymphatic Absorption of Microbial Plasmalogens in Rats

Sato Nana, Kanehama Aki, Kashiwagi Akiko, Yamada Miwa, Nishimukai Megumi.

Frontiers in Cell and Developmental Biology   10   2022.03  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

DOI

Structure-dependent absorption of atypical sphingoid long-chain bases from digestive tract into lymph

Mikami D, Sakai S, Nishimukai M, Yuyama K, Mukai K, Igarashi Y.

Lipids in Health and Disease   20 ( 1 )   2021.03  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

DOI

Cobetia sp. Bacteria, Which Are Capable of Utilizing Alginate or Waste Laminaria sp. for Poly(3-Hydroxybutyrate) Synthesis, Isolated From a Marine Environment

Moriya H, Takita Y, Matsumoto A, Yamahata Y, Nishimukai M, Miyazaki M, Shimoi H, Kawai SJ, Yamada M.

Frontiers in Bioengineering and Biotechnology   8 ( 794 )   2020.08  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

DOI

Composition of plasmalogens in serum lipoproteins from patients with non-alcoholic steatohepatitis and their susceptibility to oxidation.

Ikuta A, Sakurai T, Nishimukai M, Takahashi Y, Nagasaka A, Hui SP, Hara H, Chiba H.

Clinica Chimica Acta   493   1 - 7   2019.02  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Koji glycosylceramide commonly contained in Japanese traditional fermented foods alters cholesterol metabolism in obese mice.

Hamajima H, Tanaka M, Miyagawa M, Sakamoto M, Nakamura T, Yanagita T, Nishimukai M, Mitsutake S, Nakayama J, Nagao K, Kitagaki H.

Bioscience, Biotechnology, and Biochemistry     2018.12  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Supplemental feeding of phospholipid-enriched alkyl phospholipid from krill relieves spontaneous atopic dermatitis and strengthens skin intercellular lipid barriers in NC/Nga mice.

Watanabe N, Suzuki T, Yamazaki Y, Sugiyama K, Koike S, Nishimukai M.

Bioscience, Biotechnology, and Biochemistry     2018.12  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Influence of long-term feeding of high-fat diet on quercetin and fat absorption from the small intestine in lymph duct-cannulated rats

Makino R, Takano K, Kita K, Nishimukai M

Bioscience, Biotechnology, and Biochemistry   82 ( 11 ) 2007 - 2011   2018.07  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Association of cholesterol efflux capacity with plasmalogen levels of high-density lipoprotein: A cross-sectional study in chronic kidney disease patients

Maeba R, Kojima KI, Nagura M, Komori A, Nishimukai M, Okazaki T, Uchida S

Atherosclerosis   270   102 - 109   2018.03  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Serum ethanolamine plasmalogens improve detection of cognitive impairment among elderly with high excretion levels of urinarymyo-inositol: A cross-sectional study.

Maeba R, Araki A, Ishii K, Ogawa K, Tamura Y, Yasunaga M, Minami U, Komori A, Okazaki T, Nishimukai M, Hara H, Fujiwara Y.

Clinica Chimica Acta   453   134 - 140   2015.12  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Effect of in ovo administration of branched-chain amino acids on embryo growth and hatching time of chickens

Kita, K., Ito, RK., Sugahara, M., Kobayashi, M., Makino, R., Takahashi, N., Nakahara, H., Takahashi, K. and Nishimukai, M

Journal of Poultry Science   52   34 - 36   2014.09  [Refereed]

Academic Journal  Multiple authorship

Serum choline plasmalogens-those with oleic acid in sn-2-are biomarkers for coronary artery disease

Nishimukai, M., Maeba, R., Ikuta, A., Asakawa, N., Kamiya, K., Yamada, S., Yokota, T., Sakakibara, M., Tsutsui, H., Sakurai, T., Takahashi, Y., Hui, SP., Chiba, H., Okazaki, T. and Hara, H.

Clinica Chimica Acta   437   147 - 154   2014.07  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Proportion of nervonic acid in serum lipids is associated with serum plasmalogen levels and metabolic syndrome.

Yamazaki, Y., Kondo, K., Maeba, R., Nishimukai, M., Nezu, T. and Hara, H.

Journal of Oleo Science   63 ( 5 ) 527 - 537   2014.04  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Serum choline plasmalogens, particularly those with oleic acid in sn-2, are associated with proatherogenic state.

Nishimukai M, Maeba R, Yamazaki Y, Nezu T, Sakurai T, Takahashi Y, Hui SP, Chiba H, Okazaki T, Hara H.

Journal of Lipid Research   55 ( 5 ) 956 - 965   2014.03  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Tysnd1 deficiency in mice interferes with the peroxisomal localization of PTS2 enzymes, causing lipid metabolic abnormalities and male infertility.

Mizuno Y, Ninomiya Y, Nakachi Y, Iseki M, Iwasa H, Akita M, Tsukui T, Shimozawa N, Ito C, Toshimori K, Nishimukai M, Hara H, Maeba R, Okazaki T, Alodaib AN, Al Amoudi M, Jacob M, Alkuraya FS, Horai Y, Watanabe M, Motegi H, Wakana S, Noda T, Kurochkin IV, Mizuno Y, Schönbach C, Okazaki Y.

PLoS Genetics   9 ( 2 )   2013.02  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Lymphatic absorption of choline plasmalogen is much higher than that of ethanolamine plasmalogen in rats.

Nishimukai M, Yamashita M, Watanabe Y, Yamazaki Y, Nezu T, Maeba R, Hara H.

European Journal of Nutrition   50 ( 6 ) 427 - 436   2011.09  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Ingestion of epilactose, a non-digestible disaccharide, improves postgastrectomy osteopenia and anemia in rats through the promotion of intestinal calcium and iron absorption.

Suzuki T, Nishimukai M, Shinoki A, Taguchi H, Fukiya S, Yokota A, Saburi W, Yamamoto T, Hara H, Matsui H.

Journal of Agricultural and Food Chemistry   58 ( 19 ) 10787 - 10792   2010.10  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Suppressive effects of the marine carotenoids, fucoxanthin and fucoxanthinol on triglyceride absorption in lymph duct-cannulated rats.

Matsumoto M, Hosokawa M, Matsukawa N, Hagio M, Shinoki A, Nishimukai M, Miyashita K, Yajima T, Hara H.

European Journal of Nutrition   49 ( 4 ) 243 - 249   2010.06  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

The nondigestible disaccharide epilactose increases paracellular Ca absorption via Rho-associated kinase- and myosin light chain kinase-dependent mechanisms in rat small intestines.

Suzuki T, Nishimukai M, Takechi M, Taguchi H, Hamada S, Yokota A, Ito S, Hara H, Matsui H.

Journal of Agricultural and Food Chemistry   58 ( 3 ) 1927 - 1932   2010.02  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Improved isolation methods for mucosal leukocytes from small and large intestines in rats.

Lee JS, Oka K, Obara M, Nishimukai M, Yoo YC, Yamada K, Tsukahara T, Nakayama K, Hara H, Ishizuka S.

Bioscience, Biotechnology, and Biochemistry   73 ( 8 ) 1732 - 1740   2009.08  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Prebiotic properties of epilactose.

Watanabe J, Nishimukai M, Taguchi H, Senoura T, Hamada S, Matsui H, Yamamoto T, Wasaki J, Hara H, Ito S.

Journal of Dairy Science   91 ( 12 ) 4518 - 4526   2008.12  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Effects of epilactose on calcium absorption and serum lipid metabolism in rats.

Nishimukai M, Watanabe J, Taguchi H, Senoura T, Hamada S, Matsui H, Yamamoto T, Wasaki J, Hara H, Ito S.

Journal of Agricultural and Food Chemistry   56 ( 21 ) 10340 - 10345   2008.11  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Asaccharobacter celatus gen. nov., sp. nov., isolated from rat caecum.

Minamida K, Ota K, Nishimukai M, Tanaka M, Abe A, Sone T, Tomita F, Hara H, Asano K.

International Journal of Systematic and Evolutionary Microbiology   58 ( 5 ) 1238 - 1240   2008.05  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Enzymatic properties of cellobiose 2-epimerase from Ruminococcus albus and the synthesis of rare oligosaccharides by the enzyme.

Ito S, Taguchi H, Hamada S, Kawauchi S, Ito H, Senoura T, Watanabe J, Nishimukai M, Ito S, Matsui H.

Applied Microbiology and Biotechnology   79 ( 3 ) 433 - 441   2008.04  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Soybean phosphatidylcholine-induced enhancement of lymphatic absorption of triglyceride depends on chylomicron formation in rats.

Nishimukai M, Hara H.

Bioscience, Biotechnology, and Biochemistry   71 ( 5 ) 1192 - 1197   2007.05  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Ingestion of difructose anhydride III, a non-digestible disaccharide, improves postgastrectomy osteopenia in rats.

Shiga K, Nishimukai M, Tomita F, Hara H.

Scandinavian Journal of Gastroenterology   41 ( 10 ) 1165 - 1173   2006.10  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Supplementation of difructose anhydride III enhanced elevation of plasma equol concentrations and lowered plasma total cholesterol in isoflavone-fed rats.

Tamura A, Nishimukai M, Shigematsu N, Hara H.

British Journal of Nutrition   96 ( 3 ) 442 - 449   2006.09  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Ingestion of difructose anhydride III, a non-digestible disaccharide, prevents gastrectomy-induced iron malabsorption and anemia in rats.

Shiga K, Nishimukai M, Tomita F, Hara H.

Nutrition   22 ( 44020 ) 786 - 793   2006.07  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Enteral administration of soybean phosphatidylcholine enhances the lymphatic absorption of lycopene, but reduces that of alpha-tocopherol in rats.

Nishimukai M, Hara H.

Journal of Nutrition   134 ( 8 ) 1862 - 1866   2004.08  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Ingestion of plasmalogen markedly increased plasmalogen levels of blood plasma in rats.

Nishimukai M, Wakisaka T, Hara H.

Lipids   38 ( 12 ) 1227 - 1235   2003.12  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Enteral administration of soybean lecithin enhanced lymphatic absorption of triacylglycerol in rats.

Nishimukai, M., Hara, H. and Aoyama, Y.

British Journal of Nutrition   90 ( 3 ) 565 - 71   2003.09  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

The addition of soybean phosphatidylcholine to triglyceride increases suppressive effects on food intake and gastric emptying in rats.

Nishimukai M, Hara H, Aoyama Y.

Journal of Nutrition   133 ( 5 ) 1255 - 1258   2003.05  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Massive large bowel resection decreases bone strength and magnesium content but not calcium content of the femur in rats.

Shiga, K., Hara, H., Suzuki, T., Nishimukai, M., Konishi, A. and Aoyama, Y.

Nutrition   17 ( 5 ) 397 - 402   2001.05  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship