Published Papers - TOMITA Hiroshi

Detection of the nuclear translocation of androgen receptor using quantitative and automatic cell imaging analysis

Bai, L.; Wu, T.; Fukasawa, M.; Kashiwagi, S.; Tate, H.; Ozaki, T.; Sugano, E.; Tomita, H.; Ishii, T.; Akashi, T.; Fukuda, T

Tissue Cell   93   102631   2024.12  [Refereed]

Academic Journal  Multiple authorship

DOI

Enhanced auditory responses in visual cortex of blind rats using intrinsic optical signal imaging

Maruoka, S.; Sugano, E.; Togawa, R.; Katayama, N.; Tabata, K.; Yoshizawa, N.; Morita, R.; Takita, Y.; Ozaki, T.; Fukuda, T.; Bai, L.; Tomita, H

Sci Rep   14 ( 1 ) 24740   2024.11  [Refereed]

Academic Journal  Multiple authorship

DOI

Adipose-derived cells surpass muscle-derived cells in primary cell isolation efficacy

Bai, L.; Sawai, K.; Tani, T.; Nakai, M.; Matsusaka, H.; Ito, K.; Tomita, H.; Sugano, E.; Ozaki, T.; Fukuda, T

In Vitro Cell Dev Biol Anim   61 ( 1 ) 1 - 7   2024.10  [Refereed]

Academic Journal  Multiple authorship

DOI

Proteolysis of mitochondrial calpain-13 in cerebral ischemia-reperfusion injury

Chukai, Y.; Sudo, T.; Fukuda, T.; Tomita, H.; Sugano, E.; Ozaki, T

Biochem Biophys Rep   39   101768   2024.07  [Refereed]

Academic Journal  Multiple authorship

DOI

Altered projection-specific synaptic remodeling and its modification by oxytocin in an idiopathic autism marmoset model

Noguchi, J.; Watanabe, S.; Oga, T.; Isoda, R.; Nakagaki, K.; Sakai, K.; Sumida, K.; Hoshino, K.; Saito, K.; Miyawaki, I.; Sugano, E.; Tomita, H.; Mizukami, H.; Watakabe, A.; Yamamori, T.; Ichinohe, N

Commun Biol .   7 ( 1 ) 642   2024.05  [Refereed]

Academic Journal  Multiple authorship

DOI

Establishment of immortalized Egyptian Rousettus bat cell lines

Bai, L.; Tani, T.; Kobayashi, T.; Nouda, R.; Kanai, Y.; Sano, Y.; Takami, K.; Tomita, H.; Sugano, E.; Ozaki, T.; Kiyono, T.; Fukuda, T

FEBS Open Bio   14 ( 4 ) 598 - 612   2024.02  [Refereed]

Academic Journal  Multiple authorship

DOI

Characterization of Common Minke Whale (Balaenoptera Acutorostrata) Cell Lines Immortalized with the Expression of Cell Cycle Regulators

Sekine A. Yasunaga G. Kumamoto S. Fujibayashi S. Munirah I. Bai L. Tani T. Sugano E. Tomita H. Ozaki T. Kiyono T. Inoue-Murayama M. Fukuda T.

Adv Biol (Weinh)   8 ( 3 ) e2300227   2023.12  [Refereed]

Academic Journal  Multiple authorship

DOI

Evaluation of Local Retinal Function in Light-Damaged Rats Using Multifocal Electroretinograms and Multifocal Visual Evoked Potentials

Takita Y. Sugano E. Kitabayashi K. Tabata K. Saito A. Yokoyama T. Onoguchi R. Fukuda T. Ozaki T. Bai L. Tomita H.

Int J Mol Sci   24 ( 22 ) 16433   2023.11  [Refereed]

Academic Journal  Multiple authorship

DOI

Role of calpain-5 in cerebral ischemia and reperfusion injury

Chukai, Y.; Ito, G.; Miki, Y.; Wakabayashi, K.; Itoh, K.; Sugano, E.; Tomita, H.; Fukuda, T.; Ozaki, T

Biochim Biophys Acta Gen Subj   1868 ( 1 ) 130506   2023.11  [Refereed]

Academic Journal  Multiple authorship

DOI

Novel dicarbonyl metabolic pathway via mitochondrial ES1 possessing glyoxalase III activity

Ito, G. Tatara, Y. Itoh, K. Yamada, M. Yamashita, T. Sakamoto, K. Nozaki, T. Ishida, K. Wake, Y. Kaneko, T. Fukuda, T. Sugano, E. Tomita, H. Ozaki, T.

BBA Adv   3   100092   2023.05  [Refereed]

Academic Journal  Multiple authorship

Sheep-derived cell immortalization through the expression of cell cycle regulators and biological characterization using transcriptomes

Kikuchi, N. Matsusaka, H. Bai, L. Sano, H. Eitsuka, T. Nakagawa, K. Sugano, E. Ozaki, T. Tomita, H. Kiyono, T. Fukuda, T.

Cell Biol Int     2023.05  [Refereed]

Academic Journal  Multiple authorship

Increased lentivirus titer using ultra expression vectors

Fujibayashi, S. Kiyono, T. Endo, Y. Tani, T. Tate, H. Bai, L. Sugano, E. Tomita, H. Fukuda, T.

Anal Biochem   669   115 - 119   2023.03  [Refereed]

Academic Journal  Multiple authorship

DOI

Properties of a Single Amino Acid Residue in the Third Transmembrane Domain Determine the Kinetics of Ambient Light-Sensitive Channelrhodopsin

Hatakeyama, A. Sugano, E. Sayama, T. Watanabe, Y. Suzuki, T. Tabata, K. Endo, Y. Sakajiri, T. Fukuda, T. Ozaki, T. Tomita, H.

Int J Mol Sci   24 ( 5 )   2023.03  [Refereed]

Academic Journal  Multiple authorship

DOI

Optogenetic Therapy for Visual Restoration

Sakai, D. Tomita, H. Maeda, A.

Int J Mol Sci   23 ( 23 )   2022.11  [Refereed]

Academic Journal  Multiple authorship

DOI

Lentiviral expression of calpain-1 C2-like domain peptide prevents glutamate-induced cell death in mouse hippocampal neuronal HT22 cells

Oikawa, T. Fukuda, T. Yamashita, T. Tomita, H. Ozaki, T.

In Vitro Cell Dev Biol Anim   58 ( 4 ) 289 - 294   2022.04  [Refereed]

Academic Journal  Multiple authorship

DOI

Immortalization of cells derived from domestic dogs through expressing mutant cyclin-dependent kinase 4, cyclin D1, and telomerase reverse transcriptase

Munirah I, Ozaki T, Sekine A, Morimoto M, Sugawara M, Takada H, Sugano E, Tomita H, Kiyono T, Fukuda T

Cytotechnology   74 ( 1 ) 181 - 192   2022.02  [Refereed]

Academic Journal  Multiple authorship

DOI

Transcriptome analysis to identify the downstream genes of androgen receptor in dermal papilla cells

Furuya K, Fujibayashi S, Wu T, Takase S, Orimoto A, Sugano E, Tomita H, Kashiwagi S, Kiyono T, Ishii T, Fukuda T

BMC Genom Data   23 ( 1 ) 2   2022.01  [Refereed]

Academic Journal  Multiple authorship

DOI

Detailed chromosome analysis of wild-type, immortalized fbroblasts with SV40T, E6E7, combinational introduction of cyclin dependent kinase 4, cyclin D1, telomerase reverse transcriptase

Takada H, Miura T, Fujibayashi S, Sasaki N, Takahashi K, Sugano E, Tomita H, Ozaki T, Kiyono T, Yoshida MA, Fukuda T

In Vitro Cellular & Developmental Biology – Animal   57 ( 10 ) 998 - 1005   2021.12  [Refereed]

Academic Journal  Multiple authorship

DOI

Zinc mediates the interaction between ceruloplasmin and apo-transferrin for the efficient transfer of Fe(III) ions

Sakajiri T, Nakatsuji M, Teraoka Y, Furuta K, Ikuta K, Shibusa K, Sugano E, Tomita H, Inui T, Yamamura T

Metallomics   13 ( 12 ) mfab065   2021.12  [Refereed]

Academic Journal  Multiple authorship

DOI

Development of an optogenetic gene sensitive to daylight and its implications in vision restoration

Watanabe Y, Sugano E, Tabata K, Hatakeyama A, Sakajiri T, Fukuda T, Ozaki T, Suzuki T, Sayama T, Tomita H

NPJ Regen Med   6 ( 1 ) 64   2021.10  [Refereed]

Academic Journal  Multiple authorship

DOI

Phototoxicities Caused by Continuous Light Exposure Were Not Induced in Retinal Ganglion Cells Transduced by an Optogenetic Gene

Tabata K, Sugano E, Hatakeyama A, Watanabe Y, Suzuki T, Ozaki T, Fukuda T, Tomita H

Int J Mol Sci   22 ( 13 ) 6732   2021.06  [Refereed]

Academic Journal  Multiple authorship

DOI

The transcriptome of wild-type and immortalized corneal epithelial cells

Furuya K, Wu T, Orimoto A, Sugano E, Tomita H, Kiyono T, Kurose T, Takai Y, Fukuda T

Scientific Data   8 ( 1 ) 126   2021.05  [Refereed]

Academic Journal  Multiple authorship

DOI

Characterization of mitochondrial calpain-5

Chukai, Y. Iwamoto, T. Itoh, K. Tomita, H. Ozaki, T.

Biochim Biophys Acta Mol Cell Res ( Elsevir )  1868 ( 5 ) 118989   2021.02  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

DOI

Combinatorial expression of cell cycle regulators is more suitable for immortalization than oncogenic methods in dermal papilla cells

"Fukuda, T. Furuya, K. Takahashi, K. Orimoto, A. Sugano, E. Tomita, H. Kashiwagi, S. Kiyono, T. Ishii, T."

iScience ( Elsevir )  24 ( 1 ) 101929   2021.01  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

DOI

Geranylgeranyl acetone prevents glutamate-induced cell death in HT-22 cells by increasing mitochondrial membrane potential

Sugano, E. Endo, Y. Sugai, A. Kikuchi, Y. Tabata, K. Ozaki, T. Kurose, T. Takai, Y. Mitsuguchi, Y. Honma, Y. Tomita, H.

Eur J Pharmacol ( Elsevir )  883   173193   2020.09  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

DOI

Data on mitochondrial ultrastructure of photoreceptors in pig, rabbit, and mouse retinas

Ozaki, T. Utsumi, S. Iwamoto, T. Tanaka, M. Tomita, H. Sugano, E. Ishiyama, E. Ishida, K.

Data Brief ( Elsevir )  30   105544   2020.05  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

DOI

Presence of ES1 homolog in the mitochondrial intermembrane space of porcine retinal cells

Utsumi, S. Sakamoto, K. Yamashita, T. Tomita, H. Sugano, E. Ishida, K. Ishiyama, E. Ozaki, T.

Biochem Biophys Res Commun   524 ( 3 ) 542 - 548   2020.02  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

DOI

Neuroprotective effect of a dietary supplement against glutamate-induced excitotoxicity in retina

Kurose, T. Sugano, E. Sugai, A. Shiraiwa, R. Kato, M. Mitsuguchi, Y. Takai, Y. Tabata, K. Honma, Y. Tomita, H.

Intl J Ophthalmol   12 ( 8 ) 1231 - 1237   2019.08  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

DOI

N-Methyl-N-Nitrosourea-Induced Photoreceptor Degeneration Is Inhibited by Nicotinamide via the Blockade of Upstream Events before the Phosphorylation of Signalling Proteins

Sugano E, Tabata K, Takezawa T, Shiraiwa R, Muraoka H, Metoki T, Kudo A, Iwama Y, Nakazawa M, Tomita H

BioMed Res Intl,     3238719   2019.04  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

DOI

Overexpression of acid-Ceramidase (ASAH1) Protects Retinal Cells (ARPE19) from Oxidative Stress

Sugano E#, Edwards G, Saha S, Wilmott LA, Grambergs RC, Mondal K, Qi H, Stiles M, Tomita H#, Manda N

J Lipid Res   60 ( 1 ) 30 - 43   2018.11  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

DOI

Presence of calpain-5 in mitochondria

Iwamoto T, Ishiyama E, Ishida K, Yamashita T, Tomita H, Ozaki T

Biochem Biophys Res Commun   504 ( 2 ) 454 - 459   2018.09  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

DOI

Natronomonas pharaonis halorhodopsin Ser81 plays a role in maintaining chloride ions near the Schiff base

Sakajiri Y, Sugano E, Watanabe Y Sakajiri T, Tabata K, Kikuchi T, Tomia H

Biochem Biophys Res Commun     2018.06  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Melanocytes contribute to the vasculature of the choroid

Shibuya, H. Watanabe, R. Maeno, A. Ichimura, K. Tamura, M. Wakana, S. Shiroishi, T. Ohba, K. Takeda, K. Tomita, H. Shibahara, S. Yamamoto, H.

Genes Genet Syst   93 ( 2 ) 51 - 58   2018.04  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

DOI

The poly-cistronic expression of four transcriptional factors (CRX, RAX, NEURO-D, OTX2) in fibroblasts via retro- or lentivirus causes partial reprogramming into photoreceptor cells

Fukuda T, Ishizawa Y, Donai K, Sugano E, Tomia H

Cell Biol Int   42 ( 5 ) 608 - 614   2018.02  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Kinetic profiles of photocurrents in cells expressing two types of channelrhodopsin genes

Watanabe Y, Sugano E, Tabata K, Ozaki T, Saito T, Tamai M, Tomita H

Biochem Biophys Res Commun   496 ( 3 ) 814 - 819   2018.02  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

A Chronically Implantable Bidirectional Neural Interface for Non-Human Primates

Komatsu M, Sugano E, Tomita H, Fujii N

Front. Neurosci   11   514   2017.09  [Refereed]

Academic Journal  Multiple authorship

Thioredoxin 2 Offers Protection against Mitochondrial Oxidative Stress in H9c2 Cells and against Myocardial Hypertrophy Induced by Hyperglycemia

Li H, Xu C, Li Q, Gao X, Sugano E, Tomita H, Yang L, Shi S

Int J Mol Sci   18 ( 9 ) E1958   2017.09  [Refereed]

Academic Journal  Multiple authorship

Thioredoxin 2 Offers Protection against Mitochondrial Oxidative Stress in H9c2 Cells and against Myocardial Hypertrophy Induced by Hyperglycemia

Li H, Xu C, Li Q, Gao X, Sugano E, Tomita H, Yang L, Shi S

Int J Mol Sci   18 ( 9 ) E1958   2017.09  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

DOI

A novel rat head gaze determination system based on optomotor responses

You M, Yamane T, Tomita H, Sugano E, Akashi T

PLoS One   12 ( 4 ) e0176633   2017.04  [Refereed]

Academic Journal  Multiple authorship

Visual Responses of Photoreceptor-Degenerated Rats Expressing Two Different Types of Channelrhodopsin Gene

Sato M, Sugano E, Tabata K, Sannohe K, Watanabe Y, Ozaki T, Tamai M, Tomita H.

Sci Rep   7 ( 41210 ) 1 - 10   2017.01  [Refereed]

Academic Journal  Multiple authorship

Improved transduction efficiencies of adeno-associated virus vectors by synthetic cell-permeable peptides.

Tabata K, Sugano E, Murakami F, Yamashita T, Ozaki T, Tomita H

Biochem Biophys Res Commun   478 ( 4 ) 1732 - 1738   2016.09  [Refereed]

Academic Journal  Multiple authorship

The protection of rat retinal ganglion cells from ischemia/reperfusion injury by the inhibitory peptide of mitochondrial μ-calpain

Ozaki T, Yamashita T, Tomita H, Sugano E, Ishiguro SI.

Biochem Biophys Res Commun   478 ( 4 ) 1700 - 1705   2016.09  [Refereed]

Academic Journal  Multiple authorship

Measurement of Electroretinogram and Visually Evoked Potential in Awake Moving Mice

Tomiyama Y, Fujita K, Nishiguchi KM, Tokashiki N, Daigaku R, Tabata K, Sugano E, Tomita H, Nakazawa T.

PLoS One     2016.06  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Light induces translocation of NF-κB p65 to the mitochondria and suppresses expression of cytochrome c oxidase subunit III (COX III) in the rat retina.

Tomita H, Tabata K, Takahashi M, Nishiyama F, Sugano E.

Biochemical And Biophysical Research Communications   473 ( 4 ) 1013 - 1018   2016.05  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Local and systemic responses following intravitreous injection of AAV2-encoded modified Volvox channelrhodopsin-1 in a genetically blind rat model.

63. Sugano E, Tabata K, Takahashi M, Nishiyama F, Shimizu H, Sato M, Tamai M, Tomita H

Gene Therapy   23 ( 2 ) 158 - 166   2016.02  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Near-infrared (NIR) up-conversion optogenetics

62. Hososhima S, Yuasa H, Ishizuka T, Hoque MR, Yamashita T, Yamanaka A, Sugano E, Tomita H, Yawo H.

Scientific Reports   5   16533   2015.11  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Restoration of the majority of the visual spectrum by using modified Volvox channelrhodopsin-1.

Tomita H, Sugano E, Murayama N, Ozaki T, Nishiyama F, Tabata K, Takahashi M, Saito T, Tamai M.

Molecular Therapy   22 ( 8 ) 1434 - 1440   2014.05  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Essential Role of Thioredoxin 2 in Mitigating Oxidative Stress in Retinal Epithelial Cells

Sugano E, Murayama N, Takahashi M, Tabata K, Tamai M, Tomita H

J Ophthalmol   2013   185825   2013.11  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Decrease of ATP by mitochondrial m-calpain inhibitory peptide in the rat retinas

Ozaki T, Nakazawa M, Yamashita T, Tomita H, Ebina Y, Ishiguro SI

Cell Struct Funct   38 ( 2 ) 207 - 23   2013.08  [Refereed]

Academic Journal  Multiple authorship

Inhibitory Peptide of Mitochondrial μ-Calpain Protects against Photoreceptor Degeneration in Rhodopsin Transgenic S334ter and P23H Rats

Ozaki T, Ishiguro SI, Hirano S, Baba A, Yamashita T, Tomita H, Nakazawa M.

PLoS One   8 ( 8 ) e71650   2013.08  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Establishment of monocular-limited photoreceptor degeneration models in rabbits

Isago H, Sugano E, Murayama N, Tamai M, Tomita H

BMC Ophthalmol   17   13   2013.05  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Fabrication and In vivo Evaluation of Poly(3,4-ethylenedioxythiophene) Stimulus Electrodes for Fully Implantable Retinal Prosthesis.

Kigure C, Naganuma H, Sasaki Y, Kino H, Tomita H, Tanaka T

Jpn. J. Appl. Phys   52   04CL03   2013.04  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Optogenetically Induced Seizure and the Longitudinal Hippocampal Network Dynamics

Osawa S, Iwasaki M, Hosaka R, Matsuzaka M, Tomita H, Ishizuka T, Sugano E, Okumura E, Yawo H, Nakasato N, Tominaga T, Mushiake H

PLOS ONE   8 ( 4 ) e60928   2013.04  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Different anti-oxidant effects of thioredoxin 1 and thioredoxin 2 in retinal epithelial cells

Sugano E, Isago H, Murayama N, Tamai M, Tomita H

Cell structure and Function   38 ( 1 ) 81 - 88   2013.03  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Intravitreal injection or topical eye-drop application of a μ-calpain C2L domain peptide protects against photoreceptor cell death in Royal College of Surgeons' rats, a model of retinitis pigmentosa.

Ozaki T, Nakazawa M, Yamashita T, Sorimachi H, Hata S, Tomita H, Isago H, Baba A, Ishiguro SI

Biochim Biophys Acta   1822 ( 11 ) 1783 - 1795   2012.08  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

DOI

Notch signaling pathway regulates proliferation and differentiation of immortalized Muller cells under hypoxic conditions in vitro

Wang Z, Sugano E, Isago H, Hiroi T, Tamai M, Tomita H

Neuroscience   214 ( 12 ) 171 - 180   2012.07  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Age-dependent differences in recovered visual responses in Royal College of Surgeons rats transduced with the Channelrhodopsin-2 gene

Isago H, Sugano E, Wang Z, Murayama N, Tamai M, Tomita H

J. Mol. Neurosci   46 ( 2 ) 393 - 400   2012.02  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Differentiation of neuronal cells from NIH/3T3 fibroblasts under defined conditions

Wang Z, Sugano E, Isago H, Hiroi T, Tamai M, Tomita H

Development Growth and Differentiation   53 ( 3 ) 357 - 65   2011.04  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Immune responses to adeno-associated virus type 2 encoding channelrhodopsin-2 in a genetically blind rat model for gene therapy

Sugano E, Isago H, Wang Z, Murayama N, Tamai M, Tomita H

Gene Therapy   18 ( 3 ) 266 - 74   2011.03  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Dissecting a Role for Melanopsin in Behavioural Light Aversion Reveals a Response Independent

Semo M, Gias C, Ahmado A, Sugano E, Allen A, Lawrence JM, Tomita H, Coffey PJ, Vugler A

PLoS ONE   29 ( 5 ) e15009   2010.11  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Channelrhodopsin-2 gene transduced into retinal ganglion cells restores functional vision in genetically blind rats

Tomita H, Sugano E, Isago H, Hiroi T, Wang Z, Ohta E, Tamai M

Exp. Eye Res   90   426 - 436   2010.03  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Visual properties of transgenic rats harboring the channelrhodopsin-2 gene regulated by the Thy-1.2 promoter

Tomita H, Sugano E, Fukazawa Y, Isago H, Sugiyama Y, Hiroi T, Ishizuka T, Mushiake H, Kato M, Hirabayashi M, Shigemoto R, Yawo H, Tamai M

PLoS ONE     2009.11  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Molecular determinants differentiating photocurrent properties of two channelrhodopsins from chlamydomonas

Wang H, Sugiyama Y, Hikima T, Sugano E, Tomita H, Takahashi T, Ishizuka T, Yawo H

J. Biol. Chem   284   5685 - 5696   2009.02  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

BDNF increases the phagocytic activity in cultured iris pigment epithelial cells

Yoshida H, Tomita H, Sugano E, Isago H, Ishiguro S, Tamai M.

Cell Struct. Funct   33   21 - 26   2008.02  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Power supply system using electromagnetic induction for three-dimensionally stacked retinal prosthesis chip

Komiya K, Kobayashi R, Kobayashi T, Sato K, Fukushima T, Tomita H, Kurino H, Tanaka T, Tamai M, Koyanagi M

Jpn. J. Appl. Phys   47   3244 - 3247   2008.01  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Characteristics of mitochondrial calpains

Ozaki T, Tomita H, Tamai M, Ishiguro S

J. Biochem   142   365 - 376   2007.09  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Restoration of visual response in aged dystrophic RCS rats using AAV-mediated channelopsin-2 gene transfer

Tomita H, Sugano E, Yawo H, Ishizuka T, Isago H, Narikawa S, Kugler S, Tamai M

Invest. Ophthalmol. Vis. Sci   48   3821 - 3826   2007.08  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Retinal ganglion cell protection by 17-beta-estradiol in a mouse model of inherited glaucoma

Zhou X, Li F, Ge J, Sarkisian SR, Jr, Tomita H, Zaharia A, Chodosh J, Cao W

Dev Neurobiol   67   603 - 616   2007.04  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Hypothermia protects cultured human retinal pigment epithelial cells against indocyanine green toxicity

Kunikata H, Tomita H, Abe T, Murata H, Sagara Y, Sato H, Wada Y, Fuse N, Nakagawa Y, Tamai M, Nishida K

J. Ocul. Pharmacol. Ther   23   35 - 39   2007.02  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Evaluation of Platinum-Black Stimulus Electrode Array for Electrical Stimulation of Retinal Cells in Retinal Prosthesis System

Watanabe T, Kobayashi R, Komiya K, Fukushima T, Tomita H, Sugano E, Kurino H, Tanaka T, Tamai M, Koyanagi M.

Jpn. J. Appl. Phys   46   2785 - 2791   2007.01  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Nonredundant role of Akt2 for neuroprotection of rod photoreceptor cells from light-induced cell death

Li G, Anderson RE, Tomita H, Adler R, Liu X, Zack DJ, Rajala RV

J. Neurosci   27   203 - 211   2007.01  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Nitric oxide-induced accumulation of lipofuscin-like materials is caused by inhibition of cathepsin S

Sugano E, Tomita H, Ishiguro S, Isago H, Tamai M

Curr. Eye Res   31   607 - 616   2006.07  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Recombinant AAV-transduced iris pigment epithelial cell transplantation may transfer vector to native RPE but suppress systemic dissemination

Yoshioka Y, Abe T, Wakusawa R, Moriya T, Mochizuki S, Saigo Y, Saito T, Murata H, Tokita Y, Iseya T, Sugano E, Tomita H, Sagara Y, Tamai M

Invest. Ophthalmol. Vis. Sci   47   745 - 752   2006.02  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Evaluation of indocyanine green toxicity to rat retinas

Sato Y, Tomita H, Sugano E, Isago H, Yoshida M, Tamai M.

Ophthalmologica   220   153 - 158   2006.01  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Evaluation of Electrical Stimulus Current Applied to Retina Cells for Retinal Prosthesis

Motonami K, Watanabe T, Deguchi J, Fukushima T, Tomita H, Sugano E, Sato M, Kurino H, Tamai M, Koyanagi M.

Jpn. J. Appl. Phys   45   3784 - 3788   2006.01  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Involvement of inflammation, degradation, and apoptosis in a mouse model of glaucoma

Zhou X, Li F, Kong L, Tomita H, Li C, Cao W

J. Biol. Chem   280   31240 - 31248   2005.09  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Establishment of effective methods for transducing genes into iris pigment epithelial cells by using adeno-associated virus type 2

Sugano E, Tomita H, Ishiguro S, Abe T, Tamai M

Invest. Ophthalmol. Vis. Sci   46   3341 - 3348   2005.03  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Deleted in polyposis 1-like 1 gene (Dp1l1): a novel gene richly expressed in retinal ganglion cells

Sato H, Tomita H, Nakazawa T, Wakana S, Tamai M

Invest. Ophthalmol. Vis. Sci   46   791 - 796   2005.03  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Mechanism of protection from light-induced retinal degeneration by the synthetic antioxidant phenyl-N-tert-butylnitrone

Tomita H, Kotake Y, Anderson RE

Invest. Ophthalmol. Vis. Sci   46   427 - 434   2005.02  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Photoreceptor protection by iris pigment epithelial transplantation transduced with AAV-mediated brain-derived neurotrophic factor gene

Hojo M, Abe T, Sugano E, Yoshioka Y, Saigo Y, Tomita H, Wakusawa R, Tamai M

Invest. Ophthalmol. Vis. Sci   45   3721 - 3726   2004.10  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Transplantation of transduced retinal pigment epithelium in rats

Saigo Y, Abe T, Hojo M, Tomita H, Sugano E, Tamai M

Invest. Ophthalmol. Vis. Sci   45   1996 - 2004   2004.01  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Expression and functional properties of unique inward rectifier K+ channel Kir7.1 in the porcine iris and retinal pigment epithelium

Yasuda K, Shimura M, Nakazawa T, Sato H, Tomita H, Sugano E, Tamai M

Curr. Eye Res   27   279 - 287   2003.11  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Comparative study of cathepsins D and S in rat IPE and RPE cells

Sugano E, Tomita H, Abe T, Yamashita A, Tamai M

Exp. Eye Res   26   55 - 63   2003.08  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Distribution of rat organic anion transporting polypeptide-E (oatp-E) in the rat eye

Ito A, Yamaguchi K, Tomita H, Suzuki T, Onogawa T, Sato T, Mizutamari H, Mikkaichi T, Nishio T, Unno M, Sasano H, Abe T, Tamai M

Invest. Ophthalmol. Vis. Sci   44   4877 - 4884   2003.03  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Intrinsic activation of PI3K/Akt signaling pathway and its neuroprotective effect against retinal injury.

Nakazawa T, Shimura M, Tomita H, Akiyama H, Yoshioka Y, Kudou H, Tamai M

Curr. Eye Res   26 ( 1 ) 55 - 63   2003.01  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Transgenic rd mice harboring axokine gene by Rpe65 gene promoter does not rescue photoreceptor degeneration

Abe T, Yoshioka Y, Tomita H, Saigo Y, Udono T, Shibahara S, Tamai M

Adv. Exp. Med. Biol   533   403 - 406   2003.01  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

HLF/HIF-2alpha is a key factor in retinopathy of prematurity in association with erythropoietin

Morita M, Ohneda O, Yamashita T, Takahashi S, Suzuki N, Nakajima O, Kawauchi S, Ema M, Shibahara S, Udono T, Tomita H, Tamai M, Sogawa K, Yamamoto M, Fujii-Kuriyama Y

EMBO J   22   1134 - 1146   2003.01  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Increased expression of glutamate binding protein mRNA in rat retina after ischemia-reperfusion injury

Aikawa H, Tomita H, Ishiguro S, Nishikawa S, Sugano E, Tamai M

Tohoku J. Exp. Med   199   25 - 33   2003.01  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Protective effect against ischemia and light damage of iris pigment epithelial cells transfected with the BDNF gene

Kano T, Abe T, Tomita H, Sakata T, Ishiguro S, Tamai M

Invest. Ophthalmol. Vis. Sci   43   3744 - 3753   2002.12  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Effect of betaxolol on aspartate aminotransferase activity in hypoxic rat retina in vitro

Endo S, Tomita H, Ishiguro S, Tamai M

Jpn. J. Pharmacol   90   121 - 124   2002.12  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Mitogen-activated protein kinase inhibitor, PD98059, inhibits rat retinal pigment epithelial cell replication by cell cycle arrest

Yamaguchi K, Tomita H, Sugano E, Nakazawa T, Tamai M

Jpn. J. Ophthalmol   46   634 - 639   2002.11  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Presence of mitogen-activated protein kinase in retinal Muller cells and its neuroprotective effect ischemia-reperfusion injury

Akiyama H, Nakazawa T, Shimura M, Tomita H, Tamai M

Neuroreport   13   2103 - 2107   2002.11  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Nipradilol inhibits apoptosis by preventing the activation of caspase-3 via S-nitrosylation and the cGMP-dependent pathway

Tomita H, Nakazawa T, Sugano E, Abe T, Tamai M

Eur. J. Pharmacol   452   263 - 268   2002.10  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Neuroprotective effect of nipradilol on axotomized rat retinal ganglion cells

Nakazawa T, Tomita H, Yamaguchi K, Sato Y, Shimura M, Kuwahara S, Tamai M

Curr. Eye Res   24   114 - 122   2002.02  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Delayed-onset ataxia in mice lacking alpha -tocopherol transfer protein: model for neuronal degeneration caused by chronic oxidative stress

Yokota T, Igarashi K, Uchihara T, Jishage K, Tomita H, Inaba A, Li Y, Arita M, Suzuki H, Mizusawa H, Arai H

Proc Natl Acad Sci U S A   98   15185 - 15190   2001.12  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Changes of phagocytic capacity in basic fibroblast growth factor-transfected iris pigment epithelial cells in rats

Sakuragi M, Tomita H, Abe T, Tamai M

Curr. Eye Res   23   185 - 191   2001.09  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Müller Cells in the Preconditioned Retinal Ischemic Injury Rat

Nishiyama T, Nishikawa S, Tomita H, Tamai M

Tohoku J. Exp. Med   191   221 - 232   2000.08  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Auto iris pigment epithelial cell transplantation in patients with age-related macular degeneration: short-term results

Abe T, Yoshida M, Tomita H, Kano T, Sato M, Wada Y, Fuse N, Yamada T, Tamai M

Tohoku J. Exp. Med   191   7 - 20   2000.05  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Autologous iris pigment epithelial cell transplantation in monkey subretinal region.

Abe T, Tomita H, Kano T, Yoshida M, Ohashi T, Nakamura Y, Nishikawa S, Tamai M

Curr. Eye Res   20   268 - 275   2000.04  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Ceramide-induced cell death in cultured rat retinal pigment epithelial cells

Tomita H, Abe T, Tamai M

Tohoku J. Exp. Med   190   223 - 229   2000.03  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Functional analysis after auto iris pigment epithelial cell transplantation in patients with age-related macular degeneration

Abe T, Yoshida M, Tomita H, Kano T, Nakagawa Y, Sato M, Wada Y, Fuse N, Yamada T, Tamai M

Tohoku J. Exp. Med   189   295 - 305   1999.12  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Cytokine gene expression after subretinal transplantation

Abe T, Takeda Y, Yamada K, Akaishi K, Tomita H, Sato M, Tamai M

Tohoku J. Exp. Med   189   179 - 189   1999.11  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Characterization of iris pigment epithelial cell for auto cell transplantation

Abe T, Tomita H, Ohashi T, Yamada K, Takeda Y, Akaishi K, Yoshida M, Sato M, Tamai M.

Cell Transplant   8   501 - 510   1999.09  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

Changes of GABA metabolic enzymes in acute retinal ischemia

Kobayashi N, Ishiguro S, Tomita H, Nishikawa S, Tamai M

Exp. Eye Res   69   91 - 96   1999.07  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

DOI

Gene expression of the phosducin-like protein in the retina

Abe T, Tomita H, Tamai M.

Ophthalmic Res   30 ( 2 ) 74 - 83   1998.12  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

DOI

Increased expression of low-affinity NGF receptor in rat retinal Muller cells after ischemia and reperfusion.

Tomita H, Ishiguro S, Abe T, Tamai M

Cell Struct. Funct   23   201 - 207   1998.08  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

DOI

Administration of nerve growth factor, brain-derived neurotrophic factor and insulin-like growth factor-II protects phosphate-activated glutaminase in the ischemic and reperfused rat retinas

Tomita H, Ishiguro S, Abe T, Tamai M

Tohoku J. Exp. Med   187   227 - 236   1993.03  [Refereed]

Bulletin of University, Institute, etc.  Multiple authorship

DOI